Cytotoxic Sesquiterpene Coumarins from the Roots of Heptaptera cilicica
نویسندگان
چکیده
منابع مشابه
Cholinesterase Inhibition and Molecular Docking Studies of Sesquiterpene Coumarin Ethers from Heptaptera cilicica
Five sesquiterpene coumarin ethers: umbelliprenin, umbelliprenin-10',11'-monoepoxide, conferone, mogoltacin and feselol were isolated from the fruits of Heptaptera cilicica. Their structures were identified by means of spectroscopic methods. AChE and BuChE inhibitory activities of the compounds were determined by molecular docking method which were confirmed by in vitro experiments. According t...
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Objective: The genus of Ferula belongs to the tribe Peucedaneae, subfamily of Apioideae and family of Umbelliferae with 133 species distributed throughout the Mediterranean area and central Asia, especially in the former USSR and neighboring countries such as Iran. The popular Persian name of the most of these species is “Koma”. In this research we tried to isolate and elucidate the structure o...
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Neuroinflammation mediated by microglia cells plays a critical role in the development of Alzheimer's disease. To identify novel natural neuroinflammation inhibitors, a bioactivity-guided phytochemical research was performed on the traditional Chinese medicine "Awei", that exhibited a significant inhibitory effect on nitric oxide production in over-activated microglia cells. The research identi...
متن کاملnew sesquiterpene coumarin from the roots of ferula latisecta
objective: the genus of ferula belongs to the tribe peucedaneae, subfamily of apioideae and family of umbelliferae with 133 species distributed throughout the mediterranean area and central asia, especially in the former ussr and neighboring countries such as iran. the popular persian name of the most of these species is “koma”. in this research we tried to isolate and elucidate the structure o...
متن کاملBadrakemonin, a New Eremophilane-Type Sesquiterpene from the Roots of Ferula badrakema Kos.-Pol.
Phytochemical investigation of the dichloromethane extract of the dried roots of Ferula badrakema resulted in the identification of one new and six known compounds. Known compounds were sesquiterpene coumarins: mogoltacin, feselol, badrakemin acetate, ferocaulidin, conferone and conferol acetate. The new compound was a sesquiterpene, named badrakemonin. The structures of these compounds were el...
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ژورنال
عنوان ژورنال: Records of Natural Products
سال: 2021
ISSN: 1307-6167
DOI: 10.25135/rnp.242.21.02.1990